Browsing by Author "Ozdemir, Oztuerk"
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Alterations in Promoter Methylation Status of Tumor Suppressor HIC1, SFRP2, and DAPK1 Genes in Prostate Carcinomas
Kilinc, Devran; Ozdemir, Oztuerk; Ozdemir, Semra; Korgali, Esat; Koksal, Binnur; Uslu, Atilla; Gultekin, Yener E. (MARY ANN LIEBERT INC, 2012)Hypermethylated genomic DNA is a common feature in tumoral tissues, although the prevalence of this modification remains poorly understood. We aimed to determine the frequency of five tumor suppressor (TS) genes in prostate ... -
Epigenetic Inactivation of Tumor Suppressor SFRP2 and Point Mutation in KRAS Proto-Oncogene in Fistula - Associated Mucinous Type Anal Adenocarcinoma: Report of Two Cases
Sen, Metin; Ozdemir, Oztuerk; Turan, Mustafa; Arici, Sema; Yildiz, Fazilet; Koksal, Binnur; Goze, Fahrettin (JAPAN SOC INTERNAL MEDICINE, 2010)The secreted frizzled-related proteins (SFRPs) genes are unmethylated in normal colorectal mucosa tissue but abberant methylation profiles can be detected in colorectal cancer (CRC), adenomas, and in aberrant crypt foci. ...